
Allergan Botox® (onabotulinumtoxinA)
المواصفات الرئيسية
- Active ingredient
- onabotulinumtoxinA, the original branded botulinum toxin type A with the largest global safety registry
- Mechanism
- blocks acetylcholine release at the neuromuscular junction (muscle protocols) and at cholinergic sympathetic nerve terminals supplying eccrine sweat glands (hyperhidrosis protocols)
- Onset
- muscle protocols 1-2 weeks, hyperhidrosis within 1 week (Lowe 2023, PMID 37499084)
- Duration
- muscle 4-6 months, axillary hyperhidrosis 4-7 months per level A evidence (Lakraj 2013, PMID 23612753)
- Typical body protocols
- trapezius 100-200 U bilateral, calf 100-200 U bilateral, axillary ~50 U per side; biceps / triceps off-label individualized
- Delight policy
- 400-unit cumulative cap per single treatment day across all zones

